DocumentCode :
1487493
Title :
Direct Identification of Bacteria in Blood Culture Samples Using an Electronic Nose
Author :
Trincavelli, Marco ; Coradeschi, Silvia ; Loutfi, Amy ; Söderquist, Bo ; Thunberg, Per
Author_Institution :
Center for Appl. Autonomous Sensor Syst., Orebro Univ., Orebro, Sweden
Volume :
57
Issue :
12
fYear :
2010
Firstpage :
2884
Lastpage :
2890
Abstract :
In this paper, we introduce a method for identification of bacteria in human blood culture samples using an electronic nose. The method uses features, which capture the static (steady state) and dynamic (transient) properties of the signal from the gas sensor array and proposes a means to ensemble results from consecutive samples. The underlying mechanism for ensembling is based on an estimation of posterior probability, which is extracted from a support vector machine classifier. A large dataset representing ten different bacteria cultures has been used to validate the presented methods. The results detail the performance of the proposed algorithm and show that through ensembling decisions on consecutive samples, significant reliability in classification accuracy can be achieved.
Keywords :
blood; cellular biophysics; electronic noses; medical computing; microorganisms; patient diagnosis; probability; support vector machines; bacteria cultures; bacteria direct identification; electronic nose; gas sensor array; human blood culture samples; patient diagnosis; posterior probability; support vector machine classifier; Antibiotics; Blood; Computerized monitoring; Data mining; Electronic noses; Gas detectors; Microorganisms; Sensor arrays; Support vector machine classification; Support vector machines; Bacteria identification; electronic nose; sepsis; Algorithms; Artificial Intelligence; Bacteremia; Bacteria; Bacteriological Techniques; Biosensing Techniques; Blood; Gases; Humans; Odors; Pattern Recognition, Automated; Reproducibility of Results; Signal Processing, Computer-Assisted;
fLanguage :
English
Journal_Title :
Biomedical Engineering, IEEE Transactions on
Publisher :
ieee
ISSN :
0018-9294
Type :
jour
DOI :
10.1109/TBME.2010.2049492
Filename :
5462872
Link To Document :
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