Title :
MEMS-Based Dual-Axes Confocal Microendoscopy
Author :
Piyawattanametha, Wibool ; Wang, Thomas D.
Abstract :
In this paper, we demonstrate a miniature, near-infrared microscope (λ = 785 nm) that uses a novel dual-axes confocal architecture. Scalability is achieved with postobjective scanning, and a microelectromechanical systems mirror provide real-time (>4 Hz) in vivo imaging. This instrument can achieve subcellular resolution with deep tissue penetration and large field of view. An endoscope-compatible version can image digestive tract epithelium to guide tissue biopsy and monitor therapy.
Keywords :
bioMEMS; biological tissues; endoscopes; image resolution; micro-optomechanical devices; micromirrors; optical microscopes; optical microscopy; MEMS; deep tissue penetration; digestive tract epithelium; dual-axes confocal microendoscopy; microelectromechanical systems; miniature near-infrared microscope; mirror; real-time in vivo imaging; subcellular resolution; therapy; tissue biopsy; wavelength 785 nm; Fluorescence; imaging; medical diagnosis; microelectromechanical devices; microscopy; mirrors;
Journal_Title :
Selected Topics in Quantum Electronics, IEEE Journal of
DOI :
10.1109/JSTQE.2009.2032785
