Title :
Three-dimensional computation of light scattering from cells
Author :
Dunn, Andrew ; Richards-Kortum, Rebecca
Author_Institution :
Dept. of Electr. & Comput. Eng., Texas Univ., Austin, TX, USA
fDate :
12/1/1996 12:00:00 AM
Abstract :
Using the finite-difference time-domain method, three-dimensional scattering patterns are computed for cells containing multiple organelles. The scattering cross section and average cosine of the scattering angle are computed for cells as a function of volume fraction of melanin granules and mitochondria. Results show that small organelles play a significant role in light scattering from cells, and the volume fraction of organelles affects both the total amount of scattered light and the angular distribution of scattered light
Keywords :
Maxwell equations; biomedical imaging; cellular biophysics; finite difference time-domain analysis; laser applications in medicine; light scattering; angular distribution; cells; diagnostic optical imaging; finite-difference time-domain method; light scattering; melanin granules; mitochondria; multiple organelles; scattering angle average cosine; small organelles; three-dimensional computation; three-dimensional scattering patterns; volume fraction; Biomedical optical imaging; Cells (biology); Electromagnetic scattering; Finite difference methods; High-resolution imaging; Light scattering; Mie scattering; Optical refraction; Optical scattering; Time domain analysis;
Journal_Title :
Selected Topics in Quantum Electronics, IEEE Journal of
DOI :
10.1109/2944.577313
