Title :
Optical coherence-gated imaging of biological tissues
Author :
Pan, Y. ; Lankenou, E. ; Welzel, J. ; Birngruber, R. ; Engelhardt, R.
Author_Institution :
Medizinisches Laserzentrum Lubeck, Germany
fDate :
12/1/1996 12:00:00 AM
Abstract :
We present optical coherence-gated tomography (OCT) in turbid biological tissues. The fast OCT system that is used in this study is a single-mode fiber-optic interferometer with low-coherence light at 830 nm which can perform a cross-sectional image of 250-600 pixels in a few seconds. Preliminary results suggest that OCT can provide high-resolution imaging in low-scattering and high-scattering superficial tissues. In vitro imaging of porcine cornea after being coagulated with a laser shows that OCT is a promising tool for the evaluation of pathological structures in low-scattering tissue. This technique can also be used to diagnose disease in high-scattering tissues like bladder and living skin. In addition, 50 MHz ultrasound images and histological pictures are presented for comparison with OCT
Keywords :
biomedical imaging; biomedical ultrasonics; eye; fibre optic sensors; image resolution; infrared imaging; light coherence; light interferometers; light scattering; optical tomography; skin; turbidity; 250 to 600 pixel; 50 MHz; 830 nm; biological tissues; bladder; cross-sectional image; disease diagnosis; fast OCT system; high-resolution imaging; high-scattering superficial tissues; histological pictures; in vitro imaging; laser coagulation; living skin; low-coherence light; low-scattering superficial tissues; optical coherence-gated imaging; optical coherence-gated tomography; pathological structures; porcine cornea; single-mode fiber-optic interferometer; turbid biological tissues; ultrasound images; Biological tissues; Biomedical optical imaging; Cornea; High-resolution imaging; In vitro; Optical imaging; Optical interferometry; Pixel; Tomography; Ultrasonic imaging;
Journal_Title :
Selected Topics in Quantum Electronics, IEEE Journal of
DOI :
10.1109/2944.577332
