Title :
Simulations of the behavior of synaptically driven neurons via time-invariant circuit models
Author :
Storace, Marco ; Bove, Marco ; Grattarola, Massimo ; Parodi, Mauro
Author_Institution :
Dept. of Biophys. & Electron. Eng., Genoa Univ., Italy
Abstract :
Describes computer simulations of the behavior of Hodgkin-Huxley neurons, based on a redefinition of membrane and synaptic connections as time-invariant circuit elements. Examples are given showing that this self-consistent equivalent circuit representation allows very efficient computer simulations and could facilitate the introduction of detailed biological neurons into formal neural networks.
Keywords :
bioelectric phenomena; biology computing; biomembrane transport; digital simulation; equivalent circuits; neurophysiology; physiological models; Hodgkin-Huxley neurons; detailed biological neurons; electrophysiological behavior; formal neural networks; neuron membrane patch; self-consistent equivalent circuit representation; synaptic connections; synaptically driven neurons behavior simulation; time-invariant circuit elements; time-invariant circuit models; very efficient computer simulations; Biological system modeling; Biomembranes; Circuit simulation; Computational modeling; Computer simulation; Equivalent circuits; Neural networks; Neurons; Nonlinear equations; Voltage; Action Potentials; Animals; Cell Membrane; Computer Simulation; Humans; Models, Neurological; Neurons; Presynaptic Terminals; Synapses; Time Factors;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
