DocumentCode
1542338
Title
Conceptual design of a compact positron tomograph for prostate imaging
Author
Huber, J.S. ; Derenzo, S.E. ; Qi, J. ; Moses, W.W. ; Huesman, R.H. ; Budinger, T.F.
Author_Institution
Lawrence Berkeley Lab., CA, USA
Volume
48
Issue
4
fYear
2001
fDate
8/1/2001 12:00:00 AM
Firstpage
1506
Lastpage
1511
Abstract
We present a conceptual design of a compact positron tomograph for prostate imaging using a pair of external curved detector banks, one placed above and one below the patient. The lower detector bank is fixed below the patient bed, and the top bank adjusts vertically for maximum sensitivity and patient access. Each bank is composed of 40 conventional block detectors, forming two arcs (44 cm minor, 60 cm major axis) that are tilted to minimize attenuation and positioned as close as possible to the patient to improve sensitivity. The individual detectors are angled to point toward the prostate to minimize resolution degradation in that region. Interplane septa extend 5 cm beyond the scintillator crystals to reduce random and scatter backgrounds. A patient is not fully encircled by detector rings in order to minimize cost, causing incomplete sampling due to the side gaps. Monte Carlo simulation (including randoms and scatter) demonstrates the feasibility of detecting and differentiating partial and whole prostate tumors with a tumor-to-background ratio of 2:1, utilizing the number of events that should be achievable with a 6-min scan after a 10 mCi injection (e.g., carbon-11 choline or fluorine-18 fluorocholine)
Keywords
Monte Carlo methods; biological organs; biomedical equipment; gamma-ray detection; positron emission tomography; solid scintillation detectors; tumours; Monte Carlo simulation; block detectors; choline tracers; coincidence imaging; compact positron tomograph; conceptual design; external curved detector banks; gamma camera; improved sensitivity; interplane septa; partial prostate tumors; prostate imaging; scintillator crystals; tumor-to-background ratio; whole prostate tumors; Attenuation; Costs; Crystals; Degradation; Detectors; Event detection; Neoplasms; Positrons; Sampling methods; Scattering;
fLanguage
English
Journal_Title
Nuclear Science, IEEE Transactions on
Publisher
ieee
ISSN
0018-9499
Type
jour
DOI
10.1109/23.958388
Filename
958388
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