Title :
Correlation of permittivity and water content during cerebral edema
Author :
Kao, H. Pin ; Cardoso, Erico Ramos ; Shwedyk, Ed
Author_Institution :
Dept. of Electr. Eng. & Med., Manitoba Univ., Winnipeg, Man., Canada
Abstract :
Correlation between the permittivity of white matter and cerebral edema was studied. A time domain reflectometer was used to measure the permittivity changes of canine cerebral white matter due to edema produced in vitro by osmosis over a frequency range of 100 MHz to 1 GHz. For all frequencies, a strong correlation was found between the water content and the dielectric constant (R≈0.86) and loss factor (R≈0.82). The results suggest that it may be possible to estimate both the tissue water content as well as the composition of the accumulated edematous fluid.
Keywords :
UHF measurement; biodiffusion; bioelectric phenomena; biological tissues; biomedical measurement; brain; osmosis; permittivity measurement; time-domain reflectometry; 100 MHz to 1 GHz; accumulated edematous fluid; canine cerebral white matter; cerebral edema; circuit model parameters; dielectric constant; in vitro produced white matter; loss factor; osmosis; permittivity; time domain reflectometry; water content; Absorption; Condition monitoring; Dielectric constant; Dielectric losses; Dielectric measurements; Frequency measurement; In vitro; Osmosis; Permittivity measurement; Time measurement; Animals; Body Water; Brain; Brain Edema; Dogs; Electric Impedance; Models, Neurological; Osmosis; Permeability;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
