Title :
Three-dimensional optical tomographic imaging of breast in a human subject
Author :
Jiang, Huabei ; Xu, Yong ; Iftimia, Nicusor ; Eggert, Julie ; Klove, Karin ; Baron, Lisa ; Fajardo, Laurie
Author_Institution :
Dept. of Phys. & Astron., Clemson Univ., SC, USA
Abstract :
We present for the first time a full three-dimensional (3-D) reconstruction of absorption images of breast from continuous-wave (cw) measurements performed on a premenopausal woman. Our 3-D optical images clearly reveal a large primary tumor as well as a small secondary tumor in a separate location of the breast. The multiple tumors identified by our 3-D optical imaging have been confirmed by the subsequent biopsy examination of the breast. Quantitative information of the optical images obtained is provided in terms of the location, size, and absorption coefficient of the tumors.
Keywords :
image reconstruction; mammography; medical image processing; optical tomography; tumours; 3-D optical images; absorption images; biopsy examination; breast; continuous-wave measurements; human subject; medical diagnostic imaging; photon migration; premenopausal woman; primary tumor; secondary tumor; three-dimensional image reconstruction; three-dimensional optical tomographic imaging; Absorption; Biomedical optical imaging; Breast biopsy; Breast neoplasms; Humans; Image reconstruction; Optical imaging; Performance evaluation; Time measurement; Tomography; Biopsy; Breast Neoplasms; Carcinoma, Ductal, Breast; Female; Finite Element Analysis; Humans; Imaging, Three-Dimensional; Infrared Rays; Mammography; Middle Aged; Models, Biological; Optics; Phantoms, Imaging; Tomography;
Journal_Title :
Medical Imaging, IEEE Transactions on