Title :
Modeling and analyzing biomolecular networks
Author :
Alur, Rajeev ; Belta, Calin ; Kumar, Vijay ; Mintz, Max ; Pappas, George J. ; Rubin, Harvey ; Schug, Jonathan
Author_Institution :
Pennsylvania Univ., Philadelphia, PA, USA
Abstract :
The authors argue for the need to model and analyze biological networks at molecular and cellular levels. They propose a computational toolbox for biologists. Central to their approach is the paradigm of hybrid models in which discrete events are combined with continuous differential equations to capture switching behavior
Keywords :
biocomputing; biomolecular electronics; discrete event simulation; stochastic systems; agents; biological networks; biomolecular networks; cellular levels; computational toolbox; discrete events; genetic circuits; hybrid models; modes; molecular levels; switching behavior; Algorithm design and analysis; Analytical models; Biological system modeling; Biological systems; Cellular networks; Genetics; Humans; Predictive models; Proteins; Switches;
Journal_Title :
Computing in Science & Engineering
DOI :
10.1109/5992.976434
