Title :
Design of an integrated potentiostat circuit for CMOS bio sensor chips
Author :
Frey, Alexander ; Jenkner, Martin ; Schienle, Meinrad ; Paulus, Christian ; Holzapfl, Birgit ; Schindler-Bauer, Petra ; Hofmann, Franz ; Kuhlmeier, D. ; Krause, Jürgen ; Albers, Jorg ; Gumbrecht, Walter ; Schmitt-Landsiedel, Doris ; Thewes, Roland
Author_Institution :
Corporate Res., Infineon Technol. AG, Munich, Germany
Abstract :
A design strategy is presented for potentiostat circuits suitable for electronic bio sensors on CMOS. Guidelines are given to guarantee stable operation under the condition of widely varying and only roughly known electrochemical parameters. A concrete design example used in a fully electronic DNA sensor array CMOS chip is shown. Measurement results with a biological analyte applied to that chip prove proper operation of the potentiostat.
Keywords :
CMOS integrated circuits; DNA; biosensors; circuit stability; electrochemical analysis; integrated circuit design; integrated circuit measurement; CMOS biosensor chips; DNA sensor array; biological analyte; circuit stability; electrochemical parameters; folded cascode amplifier; integrated potentiostat circuit; Biomedical optical imaging; Biosensors; Consumer electronics; Counting circuits; DNA; Electrodes; Optical arrays; Optical sensors; Semiconductor device measurement; Sensor arrays;
Conference_Titel :
Circuits and Systems, 2003. ISCAS '03. Proceedings of the 2003 International Symposium on
Print_ISBN :
0-7803-7761-3
DOI :
10.1109/ISCAS.2003.1206159
