Title :
Optical fiber immunosensor based on polarimetry
Author :
Kooyman, R.P.H. ; Heideman, R.G. ; Koster, R. ; Greve, J.
Author_Institution :
Dept. of Appl. Phys., Twente Univ., Enschede, Netherlands
Abstract :
The authors discuss a type of evanescent field fiber immunosensor, based upon a polarimetric detection scheme. In this method the refractive indices of the involved chemical compounds are used as reporters of the binding event; no external label molecules are required. It is demonstrated that a polarimetric setup can be used to detect the adsorption of proteins on the fiber surface.<>
Keywords :
adsorption; biological techniques and instruments; biosensors; fibre optic sensors; polarimetry; proteins; refractive index measurement; adsorption of proteins; binding event; evanescent field fiber immunosensor; fiber surface; optical fiber immunosensor; polarimetric detection; refractive indices; Optical fiber polarization; Optical fiber sensors; Optical fibers; Optical interferometry; Optical refraction; Optical sensors; Optical surface waves; Optical variables control; Optical waveguides; Polarimetry;
Conference_Titel :
Solid-State Sensors and Actuators, 1991. Digest of Technical Papers, TRANSDUCERS '91., 1991 International Conference on
Conference_Location :
San Francisco, CA, USA
Print_ISBN :
0-87942-585-7
DOI :
10.1109/SENSOR.1991.148889
