Title :
Multifunctional magnetic nanoparticles for prosthesis biofilm disruption
Author :
Taylor, Erik N. ; Webster, Thomas J.
Author_Institution :
Div. of Eng. & Orthopedics, Brown Univ., Providence, RI
Abstract :
As with all surgical procedures, implantation comes with the added risk of infection. The inability of antibacterial therapy to treat persistent infection demonstrates the need for a more advanced therapeutic approach. The goal of this study was to explore the use of iron-oxide magnetic nanoparticles (IOMN) to inhibit bacteria biofilm formation and promote bone growth at the site of prosthetic infection.
Keywords :
antibacterial activity; bone; iron compounds; magnetic particles; microorganisms; nanoparticles; orthopaedics; prosthetics; Fe3O4; antibacterial therapy; bacteria biofilm formation; bone growth; iron-oxide magnetic nanoparticle; prosthetic infection; surgical procedure; Bones; Catheters; Costs; Epidermis; Joints; Magnetic field induced strain; Microorganisms; Nanoparticles; Orthopedic surgery; Prosthetics;
Conference_Titel :
Bioengineering Conference, 2009 IEEE 35th Annual Northeast
Conference_Location :
Boston, MA
Print_ISBN :
978-1-4244-4362-8
Electronic_ISBN :
978-1-4244-4364-2
DOI :
10.1109/NEBC.2009.4967726
