Title :
In vivo intravital imaging with a dual-axes confocal microscope in skin
Author :
Ra, H. ; Piyawattanametha, W. ; Gonzalez, E. ; Kaspar, R. ; Mandella, M.J. ; Contag, C.H. ; Kino, G.S. ; Solgaard, O.
Author_Institution :
Dept. of Electr. Eng., Stanford Univ., Stanford, CA
Abstract :
In this paper, a miniaturized intravital dual-axes confocal (DAC) microscope for investigating gene transfer in skin in vivo was reported. In vivo 3-D imaging not only validates what can be observed in ex vivo tissue sections, but gives spatial and temporal information in a living specimen. This opens up new opportunities in advancing disease and treatment research in the skin.
Keywords :
bioMEMS; biomedical optical imaging; diseases; genetics; optical microscopy; skin; dual-axes confocal microscope; gene transfer; in vivo intravital imaging; skin disease; skin treatment; Animals; Fluorescence; High-resolution imaging; Image resolution; In vivo; Lenses; Micromechanical devices; Microscopy; Optical imaging; Skin;
Conference_Titel :
IEEE Lasers and Electro-Optics Society, 2008. LEOS 2008. 21st Annual Meeting of the
Conference_Location :
Acapulco
Print_ISBN :
978-1-4244-1931-9
Electronic_ISBN :
978-1-4244-1932-6
DOI :
10.1109/LEOS.2008.4688475
