• DocumentCode
    1567942
  • Title

    Investigation of hemolysis in a generic implantable device: An FDA initiative

  • Author

    Sirois, Eric ; Sun, Wei

  • Author_Institution
    Univ. of Connecticut, Storrs, CT
  • fYear
    2009
  • Firstpage
    1
  • Lastpage
    2
  • Abstract
    Computational fluid simulations were developed for a generic blood-interfacing implantable device. The simulations were analyzed to determine hemodynamic behavior within the device, including velocity profiles, the magnitude of shear stress, and pressure drop. By monitoring 100 streamlines, the total blood damage induced by the device was estimated and compared to that observed for a bioprosthetic aortic valve.
  • Keywords
    biomedical equipment; blood; haemodynamics; prosthetics; shear strength; velocity; FDA initiative; bioprosthetic aortic valve; computational fluid simulation; generic blood-interfacing implantable device; hemodynamic behavior determination; hemolysis; pressure drop; shear stress magnitude; streamline; total blood damage estimation; Analytical models; Atmospheric modeling; Computational fluid dynamics; Computational modeling; Equations; Geometry; Hemodynamics; Neck; Stress; Valves; Biomechanics; Biomedical; Computational Fluid Dynamics; Engineering; Hemolysis;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioengineering Conference, 2009 IEEE 35th Annual Northeast
  • Conference_Location
    Boston, MA
  • Print_ISBN
    978-1-4244-4362-8
  • Electronic_ISBN
    978-1-4244-4364-2
  • Type

    conf

  • DOI
    10.1109/NEBC.2009.4967732
  • Filename
    4967732
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=1567942