Title :
An LED-based miniature illumination subsystem for fluorescence sensing of neuron membrane potentials
Author :
Wang, Yu ; Sun, Yaohua ; Gan, Qiaoqiang ; Perry, Susan ; Tatic-Lucic, Svetlana ; Bartoli, Filbert
Author_Institution :
Dept. of Electr. & Comput. Eng., Lehigh Univ., Bethlehem, PA
Abstract :
A miniaturized fluorescence sensing system, incorporating proximal stacking of an LED, excitation filter and cell culturing substrate, is effective in imaging GT1-7 mouse hypothalamic neurons, and probing chemically induced changes in membrane potential.
Keywords :
biosensors; fluorescence; light emitting diodes; lighting; neurophysiology; LED; cell culturing substrate; excitation filter; fluorescence sensing; hypothalamic neurons; miniature illumination subsystem; neuron membrane potentials; proximal stacking; Biomedical optical imaging; Biomembranes; Chemicals; Fluorescence; Light emitting diodes; Lighting; Neurons; Optical filters; Optical network units; Optical sensors;
Conference_Titel :
IEEE Lasers and Electro-Optics Society, 2008. LEOS 2008. 21st Annual Meeting of the
Conference_Location :
Acapulco
Print_ISBN :
978-1-4244-1931-9
Electronic_ISBN :
978-1-4244-1932-6
DOI :
10.1109/LEOS.2008.4688543
