Title :
Design and development of enhanced extraction biosensors based on photonic crystal slabs
Author :
Ganesh, Nikhil ; Block, Ian D. ; Mathias, Patrick C. ; Zhang, Wei ; Chow, Edmond ; Cunningham, Brian T.
Author_Institution :
Micro & Nanotechnol. Lab., Univ. of Illinois at Urbana-Champaign, Urbana, IL
Abstract :
Enhanced extraction of molecular fluorescence as provided by photonic crystal slabs is studied. An enhanced extraction biosensor capable of boosting fluorescence output in the detection of the cytokine TNF-alpha by over 20x is demonstrated.
Keywords :
biosensors; fluorescence; molecular biophysics; optical design techniques; photonic crystals; proteins; biosensors; cytokine TNF-alpha; enhanced extraction; molecular fluorescence; photonic crystal slabs; Biological information theory; Biosensors; Fluorescence; Goniometers; Lattices; Optical coupling; Optical microscopy; Photonic crystals; Slabs; Surface waves; 230.5750; 300.2530;
Conference_Titel :
IEEE Lasers and Electro-Optics Society, 2008. LEOS 2008. 21st Annual Meeting of the
Conference_Location :
Acapulco
Print_ISBN :
978-1-4244-1931-9
Electronic_ISBN :
978-1-4244-1932-6
DOI :
10.1109/LEOS.2008.4688544
