Title :
Symbolic Dynamic Analysis of Heart Rate and Blood Pressure Time Series of Rats
Author :
Varga, D. ; Loncar-Turukalo, T. ; Bajic, D. ; Milutinovic, S. ; Japundzic-Zigon, N.
Author_Institution :
Univ. of Novi Sad, Novi Sad
Abstract :
Insight in complex heart rate and blood pressure interactions reveals the most important aspects of autonomic control. Our main interest was in baroreceptor reflex (BRR), the most important autonomic cardiovascular reflex. We evaluated the joint symbolic dynamics of heart rate and blood pressure variations in assessing the BRR by opening the BRR loop at different levels using pharmacological blockade of beta-adrenergic, alpha-adrenergic and M-cholinergic receptors. Experiments were done in conscious telemetred VVistar out bred male rats. The observed changes between experimental groups are promising for use of symbolic dynamic method in assessment of impaired autonomic control of the cardiovascular system.
Keywords :
cardiovascular system; medical control systems; telemetry; time series; M-cholinergic receptors; autonomic cardiovascular reflex; autonomic control; baroreceptor reflex; blood pressure time series; cardiovascular system; heart rate; impaired autonomic control; pharmacological blockade; symbolic dynamic analysis; Baroreflex; Blood pressure; Cardiology; Control systems; Heart rate; Open loop systems; Pressure control; Rats; Telemetry; Time series analysis;
Conference_Titel :
Intelligent Systems and Informatics, 2007. SISY 2007. 5th International Symposium on
Conference_Location :
Subotica
Print_ISBN :
978-1-4244-1442-0
Electronic_ISBN :
978-1-4244-1443-7
DOI :
10.1109/SISY.2007.4342650
