Manufacture and Characterisation of a Bioactive and Biodegradable Composite Developed for Bone Tissue Repair

Author

Liu, Ya ; Wang, Min

Author_Institution

Dept. of Mech. Eng., Hong Kong Univ.

fYear

2006

Firstpage

4103

Lastpage

4106

Abstract

A bioactive and biodegradable composite containing hydroxyapatite (HA) and polyhydroxybutyrate (PHB) was developed for bone tissue repair. A manufacturing process, which consisted of compounding, pelletising, drying, and injection moulding, was established for producing the composite. The HA/PHB composite containing 10, 20, 30 and 40% by volume of particulate HA was successfully made. The distribution of HA particles in the PHB matrix was examined using scanning electron microscopy (SEM). Differential scanning calorimetry (DSC) was employed to investigate the melting and crystallization behavior of both compounded and injection moulded HA/PHB composite

Keywords

biomedical materials; bone; calcium compounds; cellular biophysics; crystallisation; differential scanning calorimetry; drying; filled polymers; injection moulding; melting; particle reinforced composites; scanning electron microscopy; tissue engineering; bioactive composite; biodegradable composite; bone tissue repair; compounding; crystallization; differential scanning calorimetry; drying; hydroxyapatite; injection moulding; melting; pelletising; polyhydroxybutyrate; scanning electron microscopy; Biodegradable materials; Biological materials; Bone tissue; Crystalline materials; Crystallization; Injection molding; Manufacturing; Matrices; Raw materials; Scanning electron microscopy;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the

Conference_Location

Shanghai

Print_ISBN

0-7803-8741-4

Type

conf

DOI

10.1109/IEMBS.2005.1615365

Filename

1615365