Nonlinear analysis in treatment of intractable epilepsy with EEG biofeedback

Author

Zhao, Longlian ; Wu, Wenqing ; Liang, Zuoqing ; Hu, Guangshu

Author_Institution

Dept. of Biomed. Eng., Tsinghua Univ., Beijing

fYear

2006

Firstpage

4568

Lastpage

4571

Abstract

About 25% epilepsy patients are suffering from medically intractable epileptic seizure. Many studies have shown that electroencephalogram (EEG) biofeedback therapy has the exciting potential for seizure control. In this paper, five patients with intractable epilepsy were trained to increase the production of sensorimotor (12~15 Hz) activity and decrease the production of slow theta (4~7 Hz) activity. Nonlinear analysis are proposed to evaluate the effect of biofeedback training. In all the five patients, the complexity and approximate entropy of EEG increased significantly (P<0.05) after (about 1-month) the biofeedback treatment

Keywords

diseases; electroencephalography; entropy; feedback; medical signal processing; EEG biofeedback; approximate entropy; biofeedback treatment; complexity; electroencephalogram; intractable epilepsy; medically intractable epileptic seizure; nonlinear analysis; seizure control; sensorimotor; slow theta activity; Biological control systems; Electroencephalography; Entropy; Epilepsy; Frequency; Medical treatment; Neurofeedback; Production; Rhythm; Surgery;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the

Conference_Location

Shanghai

Print_ISBN

0-7803-8741-4

Type

conf

DOI

10.1109/IEMBS.2005.1615486

Filename

1615486