Title :
Synaptic interaction of granule cells and climbing fibre on Purkinje cell
Author :
Chalakhjan, L.M. ; Chudakov, L.I. ; Dunin-Barkowski, W.L. ; Kozhemjakin, M.B. ; Zhoukovska, N.M.
Author_Institution :
Inst. for Problems of Inf. Transmission, Acad. of Sci., Moscow, Russia
Abstract :
Experimental results obtained by microstimulation of parallel and climbing fibers (PFs and CFs) are presented. Experiments were carried out on an isolated frog cerebellum. The experiments show the changes in PF bundle stimulation efficiency in relation to a monosynaptic PC (Purkinje cell) response. CF stimulation not followed by PF stimulation leads to a reduction in PF-PC synapse efficiency in every experiment. But the combination of CF and PF simulations produces an initial reduction and subsequent increase in PF-PC synapse efficiency. Thus, the results obtained suggest that PF-PC synapse efficiency could be increased after joint activation of climbing and parallel fibers
Keywords :
brain; cellular biophysics; neural nets; neurophysiology; PF-PC synapse efficiency; Purkinje cell; climbing fibre; frog cerebellum; granule cells; microstimulation; neural nets; neurophysiology; parallel fibres; Electrodes; Fires; Frequency; Glass; Neurons; Optical fiber theory; Sugar; Tail;
Conference_Titel :
Neuroinformatics and Neurocomputers, 1992., RNNS/IEEE Symposium on
Conference_Location :
Rostov-on-Don
Print_ISBN :
0-7803-0809-3
DOI :
10.1109/RNNS.1992.268549
