• DocumentCode
    1580825
  • Title

    Optimal parameters of electroporation for gene and tissue

  • Author

    Rodamporn, Somphop

  • Author_Institution
    Dept. of Electr. Eng., Srinakharinwirot Univ., Nakhonnayok, Thailand
  • fYear
    2012
  • Firstpage
    279
  • Lastpage
    282
  • Abstract
    The mechanism of electroporation has been successfully exploited to deliver gene and drugs into tissue. Electroporation has become an important role to enhance the delivery of genes into tissue. This technique can also be effectively utilized with marginal effect on viability. Electroporation technique can also provide high transfection efficiency. Therefore, there is an increasing interest in electroporation method for delivering gene into tissue. One important area is the delivery of genes into tissues as a therapy. This paper presents the overview of optimal parameters of electroporation for gene and tissue in vivo. This article reviews the obtained results, including the background of electroporation and essential parameters for transfection. This study discusses the evidence based on the success of delivering gene in vivo and effective delivery of drugs in electroporation.
  • Keywords
    biological tissues; cellular biophysics; drug delivery systems; gene therapy; drug delivery; electroporation mechanism; electroporation technique; gene delivery; high transfection efficiency; marginal effect; optimal parameters; tissue in vivo; Electroporation; gene; tissue;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Biomedical Engineering International Conference (BMEiCON), 2011
  • Conference_Location
    Chiang Mai
  • Print_ISBN
    978-1-4577-2189-2
  • Type

    conf

  • DOI
    10.1109/BMEiCon.2012.6172070
  • Filename
    6172070