Cryogenic probe for brain surgery

Present report describes a low invasive cryogenic technique for the brain surgery. Proposed micro cryogenic probe is capable of freezing of specified volume deep inside of the brain with minimum damage of surrounding neuron tissue. Mechanical damages are minimised because of small diameter of a needle of the cryogenic probe. In addition, nonoperating cryogenic damage along the needle is eliminated because the freezing takes place precisely at a tip of cryogenic needle. Mathematical simulation and experiment show that liquid refrigerant provides the most stable freezing temperature and a size of frozen volume rigidly depends on cryogenic needle diameter and boiling point of refrigerant used. The cryogenic probe could be recommended for clinical trials.