Title :
Simulation of Pulmonary Pathophysiology During Spontaneous Breathing
Author :
Zhao, Y.C. ; Rees, S.E. ; Andreassen, S. ; Kjærgaard, S.
Author_Institution :
Center for Model-based Medical Decision Support, Aalborg Univ.
Abstract :
This paper presents a functional model of lung mechanics including a non-linear alveolar pressure volume curve and representation of the work of respiratory muscles during breathing. The model is used to simulate the response to forced inspiration and expiration, and these simulations compared to the standard results of lung function tests routinely performed in departments of lung medicine. The model can simulate the characteristics of inspiratory and expiratory flow profiles seen in normal subjects, and in patients with obstructive or restrictive diseases
Keywords :
diseases; lung; muscle; physiological models; pneumodynamics; expiratory flow profiles; forced expiration; forced inspiration; inspiratory flow profiles; lung function; lung mechanics; nonlinear alveolar pressure volume curve; obstructive diseases; pulmonary pathophysiology; respiratory muscles; restrictive diseases; spontaneous breathing; Diseases; Hospitals; Immune system; Lungs; Medical diagnostic imaging; Medical simulation; Medical tests; Muscles; Performance evaluation; Ventilation;
Conference_Titel :
Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the
Conference_Location :
Shanghai
Print_ISBN :
0-7803-8741-4
DOI :
10.1109/IEMBS.2005.1615892
