A study on image features using intensity profile for cortical dysplasia degree estimation

Cortical dysplasia is a congenital anomaly of cerebral cortex. It accompanies considerable number of pediatric intractable epilepsy patients. Therefore, it is very effective to detect cortical dysplasia lesions and to estimate dysplasia degree quantitatively in pediatric brain MR images for planning treatment. However, image features on the pediatric brain MR images of cortical dysplasia aren´t clarified. This paper proposed the estimation method using intensity profile by detecting cortical dysplasia in pediatric brain MR images. The experimental results for three subjects with cortical dysplasia showed that the proposed method detected cortical dysplasia lesions with a mean sensitivity of 90.9 %, a mean specificity of 93.1 %, and a mean efficiency of 92.0%.