Title :
The role of intracellular calcium in apoptosis of human breast and oral cancer cells induced by nanosecond pulsed electric fields
Author :
Bo Su ; Jinsong Guo ; Jue Zhang ; Jing Fang ; Yi Ding ; Shan Wu
Author_Institution :
Acad. for Adv. Interdiscipl. Studies, Peking Univ., Beijing, China
Abstract :
Many previous studies have reported the interesting facts that nanosecond pulsed electrical fields (nsPEF) could reduce tumors on mice, and there have been a few hypotheses on apoptosis pathways that induced by nsPEF. However the apoptosis mechanism has not fully been elucidated so far. In this study, we investigated the relationship between intracellular calcium burst and apoptosis of breast cancer cell MCF-7 and Oral squamous cell carcinoma (OSCC) cell Cal-27 after nsPEF treatment.
Keywords :
bioelectric phenomena; biological effects of fields; calcium; cancer; cellular effects of radiation; radiation therapy; Ca; Cal-27; MCF-7; apoptosis; breast cancer cell; intracellular calcium; intracellular calcium burst; nanosecond pulsed electric fields; nsPEF; oral cancer cells; oral squamous cell carcinoma cell; tumors; Calcium; Cancer; Educational institutions; Erbium; Fluorescence; Stress; Tumors;
Conference_Titel :
Plasma Science (ICOPS), 2013 Abstracts IEEE International Conference on
Conference_Location :
San Francisco, CA
DOI :
10.1109/PLASMA.2013.6634805
