Title :
Modeling the Diffusion of Nitric Oxide Produced by Neuronal Cells in Brain Ischemia
Author :
Yong, Yang ; Gang-Min, Ning ; Zhuo-Hui, Gan ; Xiao-Xiang, Zheng
Author_Institution :
Dept. of Biomed. Eng., Zhejiang Univ., Hangzhou
Abstract :
Mathematical models of NO diffusion were established to investigate the role of nitric oxide produced by neuronal cells in brain ischemia. Results showed that NO synthesized at early stage of brain ischemia could diffuse to a far more distant than that of a resting state. We speculate the roles of NO produced by neuronal cells in brain ischemia might have two different effects, depending on its concentration
Keywords :
biodiffusion; brain; cellular transport; neurophysiology; nitrogen compounds; physiological models; NO; brain ischemia; mathematical models; neuronal cells; nitric oxide diffusion; Biomedical engineering; Blood flow; Brain modeling; Cells (biology); Equations; Gallium nitride; Ischemic pain; Mathematical model; Mathematics; Neurons; NO modeling; brain ischemia; endothelia cell; hippocampal neuron; nitric oxide;
Conference_Titel :
Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the
Conference_Location :
Shanghai
Print_ISBN :
0-7803-8741-4
DOI :
10.1109/IEMBS.2005.1616202