Title : 
In silico design control of the trade-off balance in robustness and fragility of logical circuits using DNA nanostructures
         
        
            Author : 
Hirabayashi, Miki ; Kawamata, Ibuki ; Hagiya, Masami ; Kojima, Hiroaki ; Oiwa, Kazuhiro
         
        
            Author_Institution : 
Adv. ICT Res. Inst., Nat. Inst. of Inf. & Commun. Technol., Kobe, Japan
         
        
        
        
        
            Abstract : 
The logical computation using a self-assembly process of DNA nanostructures can provide unbreakable cryptosystems or intelligent molecular robots. Focusing on the trade-off problem between the error-free robustness for stability and the error-tolerable fragility for error correction through reconnections, we present in silico analyses and propose adjustments of indirect factors to control the balance between the two. Computer simulations are helpful to characterize target problems and search optimized solutions to improve developing systems. It is expected that our results will contribute to the construction of important platform technologies for reliable DNA applications.
         
        
            Keywords : 
biocomputing; cellular automata; control system synthesis; cryptography; error correction; logic circuits; molecular electronics; network synthesis; self-assembly; stability; DNA nanostructures; computer simulations; error correction; error-free robustness; error-tolerable fragility; in silico design control; intelligent molecular robots; logical circuits; logical computation; reconnections; reliable DNA applications; self-assembly process; target problems; trade-off balance; unbreakable cryptosystems; Automata; Computational modeling; Convergence; Cryptography; DNA; Permeability; Tiles;
         
        
        
        
            Conference_Titel : 
Nanotechnology (IEEE-NANO), 2012 12th IEEE Conference on
         
        
            Conference_Location : 
Birmingham
         
        
        
            Print_ISBN : 
978-1-4673-2198-3
         
        
        
            DOI : 
10.1109/NANO.2012.6321946