Title :
Simulation of the human cardiovascular system for real-time physical interaction with an assist device
Author :
Hanson, Ben M. ; Levesley, Martin C. ; Watterson, Kevin ; Walker, Peter G.
Author_Institution :
Leeds Univ.
Abstract :
In the development of left ventricular assist devices (LVADs), numerical simulations of the cardiovascular (CV) system have been widely used. Further, electrohydraulic simulations have been developed to evaluate the performance of a physical LVAD prototype against a numerical model of the CV system. The effects of dynamic cardiac compression (DCC) have been less well modeled. This paper considers the interaction between a DCC device and a closed-loop numerical model of the cardiovascular system, which is specifically developed. The model is operated in real-time, and interfaced to the physical assist device for realistic testing. Assist control strategies are compared: constant pressure DCC, and volume-proportional pressure to simulate cardiomyoplasty. The model shows that applying equal pressure to both ventricles causes inflation of the left ventricle
Keywords :
biomedical equipment; cardiovascular system; haemodynamics; physiological models; assist control strategy; assist device; cardiomyoplasty; closed-loop numerical model; constant pressure DCC; dynamic cardiac compression; electrohydraulic simulations; human cardiovascular system; left ventricular assist devices; real-time physical interaction; ventricle; volume-proportional pressure; Cardiology; Cardiovascular system; Electrohydraulics; Humans; Numerical models; Numerical simulation; Pressure control; Real time systems; Testing; Virtual prototyping;
Conference_Titel :
Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the
Conference_Location :
Shanghai
Print_ISBN :
0-7803-8741-4
DOI :
10.1109/IEMBS.2005.1616432
