Title :
Image Registration in Myocardial Perfusion MRI
Author :
Wong, K.K. ; Wu, E.X. ; Ng, M.C. ; Wu, Y. ; Tse, H.F. ; Lau, C.P. ; Lo, G. ; Yang, E.S.
Author_Institution :
Dept. of Radiol., Harvard Med. Sch., Boston, MA
Abstract :
In clinical first-pass myocardial perfusion studies, physiological and patient motions are inevitable. Such motions impair the sensitivity and reliability in assessing myocardial perfusion abnormalities. The current study aims to correct the misregistration of myocardium during first-pass perfusion imaging by using a normalized mutual information approach. Multi-slice registrations were performed in 15 sets of clinical data sets. The proposed registration procedure was found to be fairly robust. With such registration, ROI time courses from normal myocardium and infarcted myocardium were improved, offering potential to quantify myocardial perfusion parameters in a more reliable manner
Keywords :
biomedical MRI; cardiology; haemorheology; image registration; medical image processing; muscle; ROI time courses; image registration; infarcted myocardium; misregistration; multislice registrations; myocardial perfusion MRI; normalized mutual information; Biomedical engineering; Biomedical imaging; Hospitals; Image registration; Magnetic resonance imaging; Motion analysis; Mutual information; Myocardium; Reliability engineering; Robustness;
Conference_Titel :
Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the
Conference_Location :
Shanghai
Print_ISBN :
0-7803-8741-4
DOI :
10.1109/IEMBS.2005.1616444
