Title :
Droplet-based Microtexture Biochip System for Triglycerides and Methanol Measurement
Author :
Lin, Ming-Yu ; Yu, Chih-Sheng ; Hu, Yi-Chiuen ; Cheng, Shao-Chang ; Hu, Heng-Tsang
Author_Institution :
Instrum. Technol. Res. Center, Nat. Appl. Res. Lab.
fDate :
6/27/1905 12:00:00 AM
Abstract :
A droplet-based microfluidic system was developed for biochemical assays of triglycerides and methanol as potential applications in medical rapid diagnostics and food safety. We present a novel platform to manipulate biology reaction droplets with features of self-moving, self-mixing, and self-positioning toward the detection spot. The driving force comes from the gradient of surface tension force generated by the hydrophobic microtexture PDMS surface. We also demonstrate the experiments in water, and blood droplets running uphill to overcome the gravity. These findings support the ongoing works to develop the multifunctional biosensors in medicine and food safety
Keywords :
bioMEMS; biochemistry; blood; drops; food safety; microfluidics; molecular biophysics; patient diagnosis; surface tension; biochemical assays; biology reaction droplets; blood droplets; food safety; hydrophobic microtexture PDMS surface; medical rapid diagnostics; methanol; microfluidic; microtexture biochip system; multifunctional biosensors; surface tension force; triglycerides; Cardiac disease; Cardiovascular diseases; Medical diagnostic imaging; Methanol; Microfluidics; Rough surfaces; Safety; Silicon; Surface roughness; Surface tension; PDMS; droplet-based microfluidic system; methanol; surface tension force; triglycerides;
Conference_Titel :
Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the
Conference_Location :
Shanghai
Print_ISBN :
0-7803-8741-4
DOI :
10.1109/IEMBS.2005.1616465
