Title :
Statistical Analysis of Visual Evoked Potentials in Optic Neuritis and Ischemic Optic Neuropathy Subjects
Author :
Mukartihal, G.B. ; Radhakrishnan, S. ; Reddy, M. Ramasubba ; Ayyar, S.S.K.
Author_Institution :
Dept. of Appl. Mech., Indian Inst. of Technol. Madras, Chennai
fDate :
6/27/1905 12:00:00 AM
Abstract :
An effective and clinically relevant parameter for differentiating ischemic optic neuropathy (ION) and optic neuritis (ON) patients using the visual evoked potentials (VEPs) has been identified. In this study, statistical analysis has been carried out on time domain parameters of the VEP waveforms recorded for ION (17 patients) and ON (35 patients) groups. The ratio of the amplitude of P100 component of affected eye to fellow eye showed no significant difference between the two groups. However, the mean P100 absolute latency component of ION patients was found to be significantly (p<0.001) shorter than that of ON patients. This parameter will help the neurologist to clearly classify the diseased patients and help them in early therapy planning
Keywords :
diseases; eye; neurophysiology; statistical analysis; time-domain analysis; visual evoked potentials; P100 component; diseased patients; early therapy planning; eye; ischemic optic neuropathy; optic neuritis; statistical analysis; time domain parameters; visual evoked potentials; Biomedical electrodes; Biomedical engineering; Biomedical optical imaging; Delay; Laboratories; Nervous system; Optical recording; Particle beam optics; Statistical analysis; Stimulated emission; Ischemic optic neuropathy; Optic neuritis; P100 component; Statistical analysis; VEPs;
Conference_Titel :
Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the
Conference_Location :
Shanghai
Print_ISBN :
0-7803-8741-4
DOI :
10.1109/IEMBS.2005.1616637
