Statistical Analysis of Visual Evoked Potentials in Optic Neuritis and Ischemic Optic Neuropathy Subjects

Author

Mukartihal, G.B. ; Radhakrishnan, S. ; Reddy, M. Ramasubba ; Ayyar, S.S.K.

Author_Institution

Dept. of Appl. Mech., Indian Inst. of Technol. Madras, Chennai

fYear

2005

fDate

6/27/1905 12:00:00 AM

Firstpage

1193

Lastpage

1195

Abstract

An effective and clinically relevant parameter for differentiating ischemic optic neuropathy (ION) and optic neuritis (ON) patients using the visual evoked potentials (VEPs) has been identified. In this study, statistical analysis has been carried out on time domain parameters of the VEP waveforms recorded for ION (17 patients) and ON (35 patients) groups. The ratio of the amplitude of P100 component of affected eye to fellow eye showed no significant difference between the two groups. However, the mean P100 absolute latency component of ION patients was found to be significantly (p<0.001) shorter than that of ON patients. This parameter will help the neurologist to clearly classify the diseased patients and help them in early therapy planning

Keywords

diseases; eye; neurophysiology; statistical analysis; time-domain analysis; visual evoked potentials; P100 component; diseased patients; early therapy planning; eye; ischemic optic neuropathy; optic neuritis; statistical analysis; time domain parameters; visual evoked potentials; Biomedical electrodes; Biomedical engineering; Biomedical optical imaging; Delay; Laboratories; Nervous system; Optical recording; Particle beam optics; Statistical analysis; Stimulated emission; Ischemic optic neuropathy; Optic neuritis; P100 component; Statistical analysis; VEPs;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the

Conference_Location

Shanghai

Print_ISBN

0-7803-8741-4

Type

conf

DOI

10.1109/IEMBS.2005.1616637

Filename

1616637