Serial Time Encoded Amplified Microscopy (STEAM) for high-throughput detection of rare cells

Author

Goda, Keisuke ; Motafakker-Fard, Ali ; Tsia, Kevin K. ; Jalali, Bahram

Author_Institution

Dept. of Electr. Eng., Univ. of California, Los Angeles, CA, USA

fYear

2010

Firstpage

64

Lastpage

65

Abstract

This paper describes a new type of imaging, which is referred to as serial time encoded amplified microscopy (STEAM). The ultrafast real-time imaging capability of the STEAM camera is employed to capture fast microfluidic flow and laser ablation. Recent results are presented from STEAM-based flow cytometry, which lead towards detection of rare cells in a large population of normal cells.

Keywords

biomedical optical imaging; cellular biophysics; encoding; flow visualisation; high-speed optical techniques; laser ablation; microfluidics; optical microscopy; STEAM camera; STEAM-based flow cytometry; high-throughput detection; laser ablation; microfluidic flow; rare cells; serial time encoded amplified microscopy; ultrafast real-time imaging; Cameras; High-resolution imaging; Optical imaging; Optical microscopy; Optical pulses; Optical pumping; Optical sensors; Space vector pulse width modulation; Spatial resolution; Stimulated emission;

fLanguage

English

Publisher

ieee

Conference_Titel

Photonics Society Winter Topicals Meeting Series (WTM), 2010 IEEE

Conference_Location

Majorca

Print_ISBN

978-1-4244-5240-8

Electronic_ISBN

978-1-4244-5241-5

Type

conf

DOI

10.1109/PHOTWTM.2010.5421962

Filename

5421962