Title :
A CMOS fluorescent-based biosensor microarray
Author :
Byungchul Jang ; Peiyan Cao ; Chevalier, Amelie ; Ellington, Allison ; Hassibi, Arjang
Author_Institution :
Univ. of Texas, Austin, TX
Abstract :
In this paper, we present a fully integrated fluorescent-based biosensor microarray system that includes a transducer array, molecular capture probes, a fluorescent emission filter, readout circuitry, and in-pixel ADCs. This system is specifically designed, fabricated, and experimentally validated for DNA microarrays; nevertheless the achieved specifications are well suited for other biosensor applications.
Keywords :
CMOS integrated circuits; DNA; biosensors; fluorescence; lab-on-a-chip; molecular biophysics; CMOS biosensor microarray; DNA microarrays; biological molecule binding; biological molecule interaction; biotechnology; fluorescent emission filter; fully integrated fluorescent-based biosensor microarray system; in-pixel ADC; molecular capture probes; readout circuitry; transducer array; Biomedical measurements; Biosensors; CMOS image sensors; DNA; Diodes; Face detection; Fluorescence; Optical filters; Photodetectors; Probes;
Conference_Titel :
Solid-State Circuits Conference - Digest of Technical Papers, 2009. ISSCC 2009. IEEE International
Conference_Location :
San Francisco, CA
Print_ISBN :
978-1-4244-3458-9
DOI :
10.1109/ISSCC.2009.4977495
