Title :
Predicting protein subcellular localization based on a semi-supervised algorithm
Author :
Wang, Tong ; Lu, Hong ; Cao, Xiaoxia ; Du, Yi
Author_Institution :
Inst. of Comput. & Inf., Shanghai Second Polytech. Univ., Shanghai, China
Abstract :
This paper introduces a semi-supervised method for protein subcellular localization prediction. Feature extraction plays a key role in protein subcellular localization, and can greatly improve the performance of a classifier. In this paper we propose a novel semi-supervised dimensionality reduction method for extracting features. The experimental results show that the proposed method is efficient and feasible. Compared with other methods, our method can achieve relatively higher prediction accuracy. Particularly, it is found that semi-supervised method is superior to other methods in classification performance.
Keywords :
biochemistry; feature extraction; image classification; proteins; classifier; feature extraction; protein subcellular localization prediction; semi-supervised algorithm; semisupervised dimensionality reduction method; Classification algorithms; Educational institutions; Feature extraction; Linear programming; Prediction algorithms; Proteins; Vectors; manifold learning; protein subcellular localization; semi-supervised tearing;
Conference_Titel :
Instrumentation & Measurement, Sensor Network and Automation (IMSNA), 2012 International Symposium on
Conference_Location :
Sanya
Print_ISBN :
978-1-4673-2465-6
DOI :
10.1109/MSNA.2012.6324530