Title :
Environmental immunosensor detection for 2,4-dinitrophenol as a model compound of dioxin
Author :
Park, Jong-Won ; Kurosawa, Shigeru ; Han, Dae-Sang ; Aizawa, Hidenobu ; Yoshimoto, Minoru ; Nakamura, Chikashi ; Miyake, Jun ; Chang, Sang-Mok
Author_Institution :
Nat. Inst. of Adv. Ind. Sci. & Technol., Tsukuba, Japan
fDate :
6/23/1905 12:00:00 AM
Abstract :
We present the detection of 2,4-dinitrophenol (DNP) as a model compound of dioxin to use the competitive reaction between DNP and DNP-conjugated albumin via anti-DNP antibody immobilized quartz crystal microbalance (QCM). The present QCM method is detectable in the range 0.01 to 100 ng/mL of DNP concentration, and linear correlation is obtained from 1 to 100 ng/mL of DNP concentration
Keywords :
biochemistry; biosensors; chemical sensors; microbalances; organic compounds; pollution measurement; 2,4-dinitrophenol detection; DNP-conjugated albumin; anti-DNP antibody immobilized QCM; competitive reaction; dioxin model compound; environmental immunosensor; environmental pollutants; frequency shift; linear correlation; Chemical analysis; Electrodes; Frequency measurement; Gold; Humans; Immune system; Integrated circuit modeling; Laboratories; Photonic integrated circuits; Stress;
Conference_Titel :
Frequency Control Symposium and PDA Exhibition, 2001. Proceedings of the 2001 IEEE International
Conference_Location :
Seattle, WA
Print_ISBN :
0-7803-7028-7
DOI :
10.1109/FREQ.2001.956281
