• DocumentCode
    1634883
  • Title

    Investigating the effect of regulatory decisions in a development model

  • Author

    Haddow, Pauline C. ; Hoye, Johan

  • Author_Institution
    Dept. of Comput. & Inf. Sci., Norwegian Univ. of Sci. & Technol., Trondheim
  • fYear
    2009
  • Firstpage
    293
  • Lastpage
    300
  • Abstract
    Artificial development has been introduced by many as a means to simplify the genome of the evolutionary process and thus aid scalability of evolutionary techniques. However, this simplicity in the genome comes at the cost of complexity in the mapping. This is perhaps not so surprising when we look to biology and the complicated process of gene regulation. However, creating an artificial representation of this complicated process is far from straight forward. To simplify such a process, we need to acquire knowledge and define some form of rules to guide the creation of development models. The work presented herein investigates an existing development model, identifying which factors in the model are part of the regulatory decisions. Further, experimental work looks more closely at protein pre-conditions within the model. The results form the basis for more generalised preliminary rules for protein pre-conditions creation.
  • Keywords
    biology computing; evolutionary computation; genetics; molecular biophysics; proteins; development model; evolutionary techniques; gene regulation; genome; protein preconditions; regulatory decisions; Bioinformatics; Biological system modeling; Chemicals; Costs; DNA; Genomics; Organisms; Proteins; Scalability; Shape;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Evolutionary Computation, 2009. CEC '09. IEEE Congress on
  • Conference_Location
    Trondheim
  • Print_ISBN
    978-1-4244-2958-5
  • Electronic_ISBN
    978-1-4244-2959-2
  • Type

    conf

  • DOI
    10.1109/CEC.2009.4982961
  • Filename
    4982961