Title :
A hybrid microfluidic system for cancer diagnosis based on MEMS biosensors
Author :
Ortiz, Pedro ; Keegan, Neil ; Spoors, Julia ; Hedley, John ; Harris, Alun ; Burdess, Jim ; Burnett, Richard ; Velten, Thomas ; Biehl, Margit ; Knoll, Thorsten ; Haberer, Werner ; Solomon, Matthew ; Campitelli, Andrew ; McNeil, Calum
Author_Institution :
Newcastle Univ., Newcastle upon Tyne
Abstract :
A microfluidic system for cancer diagnosis based around a core MEMS biosensor technology is presented in this paper. The principle of the MEMS biosensor is introduced and the functionalisation strategy for cancer marker recognition is described. In addition, the successful packaging and integration of functional MEMS biosensor devices are reported herein. This ongoing work represents one of the first hybrid systems to integrate a PCB packaged silicon MEMS device into a disposable microfluidic cartridge.
Keywords :
bioMEMS; biomedical electronics; biosensors; cancer; lab-on-a-chip; microfluidics; packaging; patient diagnosis; MEMS biosensor device integration; MEMS biosensor device packaging; MEMS functionalisation; PCB packaged silicon MEMS device; cancer diagnosis; cancer marker recognition; core MEMS biosensor technology; disposable microfluidic cartridge; hybrid microfluidic system; Biomedical engineering; Biosensors; Cancer; Fluctuations; Frequency; Instruments; Microfluidics; Micromechanical devices; Packaging; Temperature sensors;
Conference_Titel :
Biomedical Circuits and Systems Conference, 2008. BioCAS 2008. IEEE
Conference_Location :
Baltimore, MD
Print_ISBN :
978-1-4244-2878-6
Electronic_ISBN :
978-1-4244-2879-3
DOI :
10.1109/BIOCAS.2008.4696943
