A hybrid microfluidic system for cancer diagnosis based on MEMS biosensors

Author

Ortiz, Pedro ; Keegan, Neil ; Spoors, Julia ; Hedley, John ; Harris, Alun ; Burdess, Jim ; Burnett, Richard ; Velten, Thomas ; Biehl, Margit ; Knoll, Thorsten ; Haberer, Werner ; Solomon, Matthew ; Campitelli, Andrew ; McNeil, Calum

Author_Institution

Newcastle Univ., Newcastle upon Tyne

fYear

2008

Firstpage

337

Lastpage

340

Abstract

A microfluidic system for cancer diagnosis based around a core MEMS biosensor technology is presented in this paper. The principle of the MEMS biosensor is introduced and the functionalisation strategy for cancer marker recognition is described. In addition, the successful packaging and integration of functional MEMS biosensor devices are reported herein. This ongoing work represents one of the first hybrid systems to integrate a PCB packaged silicon MEMS device into a disposable microfluidic cartridge.

Keywords

bioMEMS; biomedical electronics; biosensors; cancer; lab-on-a-chip; microfluidics; packaging; patient diagnosis; MEMS biosensor device integration; MEMS biosensor device packaging; MEMS functionalisation; PCB packaged silicon MEMS device; cancer diagnosis; cancer marker recognition; core MEMS biosensor technology; disposable microfluidic cartridge; hybrid microfluidic system; Biomedical engineering; Biosensors; Cancer; Fluctuations; Frequency; Instruments; Microfluidics; Micromechanical devices; Packaging; Temperature sensors;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Circuits and Systems Conference, 2008. BioCAS 2008. IEEE

Conference_Location

Baltimore, MD

Print_ISBN

978-1-4244-2878-6

Electronic_ISBN

978-1-4244-2879-3

Type

conf

DOI

10.1109/BIOCAS.2008.4696943

Filename

4696943