Title :
Measuring the impedance of a tethered bilayer membrane biosensor
Author :
Hamilton, Tara J. ; Van Schaik, André ; Cornell, Bruce
Author_Institution :
Sch. of Inf. Technol. & Electr. Eng., Univ. of Queensland, Brisbane, QLD
Abstract :
In this paper we present a method for measuring the complex impedance of a tethered bilayer membrane (tBLM). Measuring the impedance of a tBLM can involve large, nonportable, expensive instrumentation. Here we present a method of complex impedance measurement that is portable and inexpensive; requiring only a laptop or palm-pocket computer with a USB interface. The complex impedance measurement is improved by using a type of pseudorandom binary sequence (PRBS) called a maximum length sequence (MLS). This method of impedance measurement improves the resolution over conventional sinusoidal frequency sweeping methods.
Keywords :
binary sequences; bioelectric phenomena; biological techniques; biology computing; biomembranes; biosensors; computerised instrumentation; electric impedance measurement; lipid bilayers; random sequences; system buses; USB interface; electric impedance measurement; laptop computer; lipid bilayer membrane; maximum length sequence; palm-pocket computer; pseudorandom binary sequence; sinusoidal frequency sweeping method; tethered bilayer membrane biosensor; Binary sequences; Biomembranes; Biosensors; Computer interfaces; Frequency; Impedance measurement; Instruments; Multilevel systems; Portable computers; Universal Serial Bus; biosensor; complex impedance; maximum length sequence (MLS); pseudorandom binary sequence (PRBS); tethered bilayer membrane (tBLM);
Conference_Titel :
Biomedical Circuits and Systems Conference, 2008. BioCAS 2008. IEEE
Conference_Location :
Baltimore, MD
Print_ISBN :
978-1-4244-2878-6
Electronic_ISBN :
978-1-4244-2879-3
DOI :
10.1109/BIOCAS.2008.4696949
