DocumentCode
1651306
Title
Small-World Network Approach to Identify Nucleus Residues of the B1 Domain of Protein G#
Author
Li, Hai-yan ; Wang, Ji-Hua ; Zhao, Li-ling ; Dou, Xiang-Hua ; Luo, Xiu-ping
Author_Institution
Key Lab. of Biophys., Univ. of Shandong Province, Dezhou
fYear
2008
Firstpage
211
Lastpage
214
Abstract
The B1 domain of protein G is a paradigm for kinetics studies. In this work, the protein structure of GB1 is modeled as an unweighted amino acid network. We find that the unweighted amino acid network is the typical property of small-world network. The nucleus residues of GB1 are identified by the analysis of the network parameter: betweenness. The results are consistent with the previous experimental and theoretical studies.
Keywords
molecular biophysics; proteins; B1 domain; nucleus residues; protein G; protein structure; small-world network approach; unweighted amino acid network; Amino acids; Biophysics; Complex networks; Educational institutions; Kinetic theory; Lattices; Network topology; Physics; Protein engineering; Sequences;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedical Engineering, 2008. ICBBE 2008. The 2nd International Conference on
Conference_Location
Shanghai
Print_ISBN
978-1-4244-1747-6
Electronic_ISBN
978-1-4244-1748-3
Type
conf
DOI
10.1109/ICBBE.2008.57
Filename
4534937
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