Evidence for Independent Segregation of the VP6-and-NSP4-Encoding Genes in Human Group A Rotavirus G5P[6] Strains

Author

Li, Dan-Di ; Yu, Jie-mei ; Cui, Shu-xian ; Zhang, Qing ; Yuan, Xin-hui ; Zhang, Dong-liang ; Cao, Da-jiang ; Yang, Su-hua ; Li, Hui-ying ; Wang, Zhong-Shan ; Duan, Zhao-Jun

Author_Institution

Sch. of Basical Med. Sci., Jilin Univ., Changchun

fYear

2008

Firstpage

301

Lastpage

305

Abstract

VP6- and NSP4- encoding genes of human group A rotavirus strain LL3354 with rare genotypes (G5P[6]), detected from China Lulong, was characterized by reverse transcription-PCR followed by sequencing and phylogenetic analysis. LL3354 joins the major cluster of SGI rotaviruses in the VP6 phylogenetic tree, However, It was identified as NSP4 genotype B. Our results provide evidence for independent segregation of the VP6- and NSP4-encoding genes in human group A rotaviruses.

Keywords

genetic engineering; microorganisms; molecular biophysics; segregation; China Lulong; LL3354; NSP4 genotype B; NSP4-encoding gene; VP6 phylogenetic tree; VP6-encoding gene; gene sequencing; human group A rotavirus strain; independent segregation; phylogenetic analysis; reverse transcription-PCR; rotavirus G5P[6] strain; Amino acids; Animals; Capacitive sensors; Diseases; Encoding; Humans; Pathogens; Phylogeny; RNA; Strain control;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioinformatics and Biomedical Engineering, 2008. ICBBE 2008. The 2nd International Conference on

Conference_Location

Shanghai

Print_ISBN

978-1-4244-1747-6

Electronic_ISBN

978-1-4244-1748-3

Type

conf

DOI

10.1109/ICBBE.2008.77

Filename

4534957