An optical sensor for propagation analysis of Lymphocyte cell for cancer cell detection

Photonic crystal biosensors are highly sensitive devices for detection and analysis of bio-analytes that combines biological components with a physicochemical detector using phonon vibrations. Early stage cancer cell detection is currently the need of the hour. In this paper we have demonstrated a 2-dimensional grating based photonic crystal based biosensor for complete analysis of normal healthy Lymphocyte cell and its components for early stage detection of cancer. Finite Difference Time Domain (FDTD) method has been used for the analysis of the cell. MEEP and MATAB simulation tools have been used for modeling and designing of photonic crystal based sensor and the intensity levels of transmission and reflection spectrums have been observed. It has been observed from the band structure that for little change in refractive index (RI) there will be a significant shift in the frequency and hence it acts as a sensor. This indicates that it is highly sensitive for the change in refractive index and thus it can differentiate between different components of the Lymphocyte cell as well as normal and cancerous cell.