Title :
Similar Histone Acetylation Pattern of Neighboring Genes in Yeast
Author :
Deng, Yangyang ; Dai, Xianhua
Author_Institution :
Dept. of Electron. & Commun. Eng., Sun Yat-Sen Univ., Guangzhou
Abstract :
Neighboring genes were found to have a similar expression pattern in eukaryotic genome. But the reason is not clear yet. We find that immediate neighboring genes in yeast show a strong positive correlation in histone acetylation pattern. The co-modification (similar acetylation pattern) extends to neighboring pairs within 12 genes or 11 kbp on chromosomes. These results suggest that chromatin acetylation patterns may play a role in coexpression (similar expression pattern) of neighboring genes.
Keywords :
biochemistry; cellular biophysics; genetics; microorganisms; chromatin acetylation patterns; coexpression; eukaryotic genome; histone acetylation pattern; neighboring gene expression pattern; yeast; Bioinformatics; Biological cells; Fungi; Genomics; Information science; Measurement standards; Pattern analysis; Proteins; Semiconductor device measurement; Sun;
Conference_Titel :
Bioinformatics and Biomedical Engineering, 2008. ICBBE 2008. The 2nd International Conference on
Conference_Location :
Shanghai
Print_ISBN :
978-1-4244-1747-6
Electronic_ISBN :
978-1-4244-1748-3
DOI :
10.1109/ICBBE.2008.91
