Title :
Computational Identification of Two Potential ncRNAs from 48 Esophageal Carcinoma-Related Sequences
Author :
Wu, Bingli ; Xu, Liyan ; Ying, Xiaomin ; Niu, Yongdong ; Li, Wuju ; Li, Enmin
Abstract :
Forty-eight esophageal carcinoma-related sequences were analyzed by various bioinformatics tools. The results indicated that 46 sequences were holomogous to the known genes with detail functional annotations. However, two sequences did not have holomogy to all known genes. Further analysis implied that these two sequences might be noncoding RNAs (ncRNA), and one of them located in the human mitochondria. Finally, the mechanisms of their functions were discussed.
Keywords :
biology computing; cancer; cellular biophysics; genetics; medical computing; molecular biophysics; molecular configurations; RNA sequences; bioinformatics; esophageal carcinoma; genes; holomogy; human mitochondria; ncRNA; noncoding RNA; Biochemistry; Bioinformatics; Computational biology; Databases; Educational institutions; Esophagus; Genomics; Humans; RNA; Sequences;
Conference_Titel :
Bioinformatics and Biomedical Engineering, 2008. ICBBE 2008. The 2nd International Conference on
Conference_Location :
Shanghai
Print_ISBN :
978-1-4244-1747-6
Electronic_ISBN :
978-1-4244-1748-3
DOI :
10.1109/ICBBE.2008.109
