DocumentCode :
1653326
Title :
A Comparison of Validation Indices for Evaluation of Clustering Results of DNA Microarray Data
Author :
Ristevski, Blagoj ; Loshkovska, Suzana ; Dzeroski, Sasho ; Slavkov, Ivica
Author_Institution :
Dept. of Comput. Sci. & Inf., Inf. Technol. Skopje, Skopje
fYear :
2008
Firstpage :
587
Lastpage :
591
Abstract :
In this paper we assess the clustering results of gene expression (microarray) data by using different validation indices. We perform k-means clustering and evaluate the results by using three validation indices: Silhouette, Davies-Bouldin´s and our proposed BR index. For performing the experiments we use our implementation of these measures in MATLAB. From the comparison of the validation indices we can conclude that BR index has better decreasing tendency depending on the number of clusters than Davies Bouldin´s index for yeast microarray dataset.
Keywords :
DNA; biology computing; cellular biophysics; molecular biophysics; BR validation index; DNA microarray data; Davies-Bouldin validation index; MATLAB; gene expression data; k means clustering; microarray data clustering results; silhouette validation index; validation index comparison; yeast microarray dataset; Bioinformatics; Cancer; DNA; Gene expression; MATLAB; Organisms; Performance evaluation; Proteins; RNA; Sequences;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Bioinformatics and Biomedical Engineering, 2008. ICBBE 2008. The 2nd International Conference on
Conference_Location :
Shanghai
Print_ISBN :
978-1-4244-1747-6
Electronic_ISBN :
978-1-4244-1748-3
Type :
conf
DOI :
10.1109/ICBBE.2008.143
Filename :
4535023
Link To Document :
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