Title :
Application of Optimization with Scaled Conjugate Gradient Algorithm in IMRT
Author :
Wang Zhuoyu ; Zhou Linghong ; Chen Chaomin ; Lu Wenting ; Zeng Xin ; Zhu Lin
Author_Institution :
Sch. of Biomed. Eng., Southern Med. Univ., Guangzhou
Abstract :
Objective To implement the optimization of beam weight in IMRT planning optimization. Methods The treatment planning system of IMRT has been developed with SCG algorithm for determining the intensity-modulated beams and pencil beam model for dose distribution. Results A example of a lung case has been optimized by the IMRT system. The DVH shows that 97%PTV is irradiated by 95%~105% of the described dose. OAR and normal tissue are irradiated by no more than 15% and 40% respectively. Conclusion SCG algorithm implemented as an inverse planning algorithm for determining the intensity-modulated beams that will most closely generate a desired dose distribution is presented as well as a method for dose calculation in IMRT using pencil beam model.
Keywords :
dosimetry; lung; optimisation; radiation therapy; IMRT treatment planning optimization; IMRT treatment planning system; SCG algorithm; beam weight optimization; dose distribution; intensity modulated beams; intensity modulated radiation therapy; inverse planning algorithm; lung; pencil beam model; scaled conjugate gradient algorithm; Biomedical engineering; Chaos; Convolution; Cost function; Current distribution; Gradient methods; Iterative algorithms; Kernel; Lungs; Neoplasms;
Conference_Titel :
Bioinformatics and Biomedical Engineering, 2008. ICBBE 2008. The 2nd International Conference on
Conference_Location :
Shanghai
Print_ISBN :
978-1-4244-1747-6
Electronic_ISBN :
978-1-4244-1748-3
DOI :
10.1109/ICBBE.2008.183
