Application of Optimization with Scaled Conjugate Gradient Algorithm in IMRT

Author

Wang Zhuoyu ; Zhou Linghong ; Chen Chaomin ; Lu Wenting ; Zeng Xin ; Zhu Lin

Author_Institution

Sch. of Biomed. Eng., Southern Med. Univ., Guangzhou

fYear

2008

Firstpage

751

Lastpage

754

Abstract

Objective To implement the optimization of beam weight in IMRT planning optimization. Methods The treatment planning system of IMRT has been developed with SCG algorithm for determining the intensity-modulated beams and pencil beam model for dose distribution. Results A example of a lung case has been optimized by the IMRT system. The DVH shows that 97%PTV is irradiated by 95%~105% of the described dose. OAR and normal tissue are irradiated by no more than 15% and 40% respectively. Conclusion SCG algorithm implemented as an inverse planning algorithm for determining the intensity-modulated beams that will most closely generate a desired dose distribution is presented as well as a method for dose calculation in IMRT using pencil beam model.

Keywords

dosimetry; lung; optimisation; radiation therapy; IMRT treatment planning optimization; IMRT treatment planning system; SCG algorithm; beam weight optimization; dose distribution; intensity modulated beams; intensity modulated radiation therapy; inverse planning algorithm; lung; pencil beam model; scaled conjugate gradient algorithm; Biomedical engineering; Chaos; Convolution; Cost function; Current distribution; Gradient methods; Iterative algorithms; Kernel; Lungs; Neoplasms;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioinformatics and Biomedical Engineering, 2008. ICBBE 2008. The 2nd International Conference on

Conference_Location

Shanghai

Print_ISBN

978-1-4244-1747-6

Electronic_ISBN

978-1-4244-1748-3

Type

conf

DOI

10.1109/ICBBE.2008.183

Filename

4535063