FT-IR microspectroscopy of cisplatin loaded PLGA nanoparticles

Author

Portaccio, Marianna ; Menale, Ciro ; Diano, Nadia ; Mita, Damiano G. ; Lepore, Maria

Author_Institution

Dipt. di Med. Sperimentale, Seconda Univ. di Napoli, Naples, Italy

fYear

2014

fDate

12-14 May 2014

Firstpage

1

Lastpage

3

Abstract

Biodegradable polymer nanoparticles have recently received considerable attention for drug delivery. One of the most investigated system is represented by cisplatin-loaded poly-(D, L-lactic-co-glycolic)acid (PLGA) nanoparticles. FT-IR microspectroscopy has been used for characterizing these particles. In addition an univariate analysis procedure has been adopted for interpreting experimental results when the spectrum modifications are relatively weak.

Keywords

Fourier transform spectra; biodegradable materials; biomedical materials; drug delivery systems; drugs; infrared spectra; nanomedicine; nanoparticles; nanophotonics; polymer blends; FT-IR microspectroscopy; biodegradable polymer nanoparticles; cisplatin loaded PLGA nanoparticles; drug delivery; poly-(D, L-lactic-co-glycolic)acid; spectrum modifications; Atmospheric measurements; Nanoparticles; Particle measurements; FT-IR microspectroscopy; PLGA nanoparticles; cisplatin; drug delivery; univariate analysis;

fLanguage

English

Publisher

ieee

Conference_Titel

Photonics Technologies, 2014 Fotonica AEIT Italian Conference on

Conference_Location

Naples

Print_ISBN

978-8-8872-3718-4

Type

conf

DOI

10.1109/Fotonica.2014.6843959

Filename

6843959