Title :
Determination of protein titration curves using Si Nanograting FETs
Author :
Silu Zhang ; Pengyuan Zang ; Yuchen Liang ; Hu, Wenfeng
Author_Institution :
Electr. Eng. Dept., Univ. of Texas at Dallas, Richardson, TX, USA
Abstract :
This study describes a methodology of measuring protein titration curve by Si Nanograting FETs (NGFETs). Two proteins were measured with each of the titration curves showing specific characters for identification. The measurements at high ionic concentration were performed to eliminate the effect of SiO2 surface. The intrinsic protein titration curves extracted are consistent with prior researches.
Keywords :
biochemistry; biological techniques; chemical variables measurement; field effect transistors; molecular biophysics; nanobiotechnology; proteins; silicon; NGFET; Si nanograting FET; SiO2 surface; high-ionic concentration measurements; intrinsic protein titration curves; Electric potential; Field effect transistors; Mice; Proteins; Silicon; Surface treatment;
Conference_Titel :
Nanotechnology (IEEE-NANO), 2014 IEEE 14th International Conference on
Conference_Location :
Toronto, ON
DOI :
10.1109/NANO.2014.6968097