Title :
Breast carcinomas: prognosis assisted by computer image analysis
Author_Institution :
Lab. of Histology, Univ. Joseph Fourier, La Tronche, France
Abstract :
Summary form only given. The results of a study of the smears of 159 patients with invasive ductal adenocarcinomas are reported. Image cytometry of estrogen receptor immunolabeling and DNA distribution in the smears was carried out. Software was developed to analyze routine preparations and to estimate objectively the tumor heterogeneity. A calculated parameter highly correlated with biochemical assay was defined. The discrimination of four groups of tumors with significant differences in the degree of malignancy was made by combining immunolabeling and Feulgen analysis
Keywords :
computerised picture processing; medical computing; DNA distribution; Feulgen analysis; biochemical assay; cancer; computer image analysis; estrogen receptor immunolabeling; image cytometry; invasive ductal adenocarcinomas; malignancy degree; medical computing; medical prognosis; smears; software; tumor heterogeneity; Biomedical optical imaging; Breast neoplasms; Cancer; Cells (biology); DNA; Erbium; Image analysis; Immune system; Integrated optics; Medical treatment;
Conference_Titel :
Engineering in Medicine and Biology Society, 1989. Images of the Twenty-First Century., Proceedings of the Annual International Conference of the IEEE Engineering in
Conference_Location :
Seattle, WA
DOI :
10.1109/IEMBS.1989.95764
