Title :
An imaging system for automatic analysis of DNA electrophoretic gels
Author :
Haydar, L.A. ; Jaggi, B.
Author_Institution :
British Columbia Cancer Res. Centre, Vancouver, BC, Canada
Abstract :
An imaging system has been designed, implemented and tested for automatic analysis of DNA electrophoretic films. An image of a film is acquired and digitized. The DNA bands are then recognized and contoured, allowing the computation of their integrated optical densities. The imaging system is compared to the densitometer system and is shown to be superior in terms of speed, accuracy and convenience. The imaging system also displays a greater dynamic range of optical density than the densitometer does
Keywords :
DNA; biological techniques and instruments; biology computing; computerised picture processing; electrophoresis; gels; molecular biophysics; DNA bands; DNA electrophoretic gels; automatic analysis; densitometer; dynamic range; film image; imaging system; integrated optical density; Automatic testing; DNA computing; Displays; Dynamic range; Image analysis; Integrated optics; Optical computing; Optical films; Optical imaging; System testing;
Conference_Titel :
Engineering in Medicine and Biology Society, 1989. Images of the Twenty-First Century., Proceedings of the Annual International Conference of the IEEE Engineering in
Conference_Location :
Seattle, WA
DOI :
10.1109/IEMBS.1989.95767
