Title :
Rapid DNA detection via optofluidic lasers using saturation dye
Author :
Lee, Wonsuk ; Fan, Xudong
Author_Institution :
Dept. of Biomed. Eng., Univ. of Michigan, Ann Arbor, MI, USA
Abstract :
We demonstrate an optofluidic laser using the saturation dye and double-stranded DNA mixture, and develop a rapid and direct DNA detection technique relying on highly distinguishable lasing characteristics between the target DNA and the polymorphism.
Keywords :
DNA; bio-optics; bioMEMS; biological effects of laser radiation; biomolecular effects of radiation; biosensors; dyes; microfluidics; microsensors; mixtures; optical sensors; polymorphism; double-stranded DNA mixture; optofluidic lasers; polymorphism; rapid DNA detection; saturation dye; DNA; Fluorescence; Laser excitation; Laser theory; Probes; Pump lasers;
Conference_Titel :
Lasers and Electro-Optics (CLEO), 2012 Conference on
Conference_Location :
San Jose, CA
Print_ISBN :
978-1-4673-1839-6
